scRNA-sequencing data quality control

Quality control is the basic step in any single-cell sequencing data analysis. This comes in two parts. First, performing quality control on cells by removing outliers, any doublet or dead […]

Single cell proteomics

Like the field of Proteomics, Single-Cell Proteomics encompasses all aspects of protein study in single-cells, including but not limited to protein structural analysis, identification, abundance and the qualitative and quantitative […]

CAR T cells

CAR T cells are genetically modified T cells, with the ability to express special receptors called chimeric antigen receptors (CARs). CARs are designed for a specific surface protein on cancer […]

Human embryonic stem cells

Human embryonic stem cells are derived from the inner cell mass of the blastocyst stage of a human embryo. These cells are pluripotent, which means they are able to differentiate […]

Heteroplasmy

Mitochondria contain multiple copies of mitochondrial DNA (mtDNA). When all copies are identical, the mitochondria is said to exist in “homoplasmy”. Sometimes, a copy of mtDNA has a variant (e.g. […]

Gene therapy

Gene therapy is a new class of treatments that promise to treat and possibly cure many debilitating diseases. In contrast to conventional treatments, gene therapy treats the cause of the […]

Virus-like particle

Virus-like particles (VLPs) are multiprotein structures that mimic the organization and conformation of authentic native viruses but lack the viral genome, thus making them safe and effective vaccine candidates. VLPs […]

Single cell RNA Sequencing (scRNASeq)

A technique used to study gene expression in single cells. In contrast to bulk RNASeq methods, single cell RNASeq can capture gene expression information in individual cells and reveal cell-to-cell […]

Baculovirus Expression Vector System (BEVS)

BEVS is a fast and extensively used expression system in which a gene of interest is overexpressed in insect cells upon infection with a genetically modified baculovirus, in order to […]

Flow cytometry

Flow cytometry is a technology that simultaneously measures and then analyses multiple physical characteristics of single particles, usually cells, as they flow in a fluid stream through a beam of […]