Integrating scRNA-seq and scATAC-seq data
Single cell RNA sequencing (scRNA-seq) has exemplified recent advances in the anlaysis of transcriptomic heterogeneity, enabling the characterisation of gene expression in individual cells. The utility of scRNA-seq data can […]
tSNE
t-distributed stochastic neighbor embedding or more commonly referred to as tSNE is technique used to reduce the dimensions of a data set, but why is this desired? Effective data visualization […]
Perfusion
Perfusion is a type of cultivation method for cells. It is very similar in operation to a continuous stirred tank except that there is a device on the outflow that […]
Mitochondria
Mitochondria are the powerhouse of the cell. Distinctively, they contain their own DNA termed Mitochondrial DNA (mtDNA). Each mammalian cell contains thousands of copies of mtDNA. When all copies within […]
FN-Silk (Biosilk)
FN-Silk is a self-assembling spider silk functionalized with a Fibronectin to promote cell adhesion used for advanced 3D cell culture. It has been shown to be non-immunogenic and biodegradable. Cells […]
Single cell transcriptomics – a gerneric explanation of common steps
Single-cell RNA sequencing (scRNA-seq) has significantly advanced our knowledge of biological systems by studying the single cell transcriptome. Compared to bulk RNA-seq, scRNA-seq is able to study cellular heterogeneity. BDTM […]
scRNA-sequencing data quality control
Quality control is the basic step in any single-cell sequencing data analysis. This comes in two parts. First, performing quality control on cells by removing outliers, any doublet or dead […]
Inspiring the next generation of scientists – a new blog post from STACCATO ESR is live
This March our ESR4 James Clubb gave a scientific workshop to a group of five to seven year old students at an international kindergarten in Helsinki, Finland. In a new […]
3rd place in the Langen Junior Science Award
On 08 April 2022, Filippos Theofilos Charitidis (ESR9) received 3rd place in the Langen Junior Science Award for his publication on “Monitoring CAR T cell generation with a CD8-targeted lentiviral […]
STACCATO has its YouTube channel
“Video is the next wave, and scientists must be prepared for it,” says McKee in her know-how for scientists, The Scientist Videographer. YouTube is a particularly relevant platform because of […]
